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Disease pathwayKidney / Upper Tract

UPJ Obstruction

Pelviureteric junction obstruction blocks drainage from the renal pelvis into the ureter — confirmed by a diuretic renogram, and repaired (pyeloplasty) when symptoms, stones, infection or declining function appear.

Block
pelvis → ureter
+
Sign
dilated pelvis, normal ureter
+
Repair
pyeloplasty
Orientation

The big picture

At the pelviureteric junction, intrinsic narrowing (often congenital) or an external crossing lower-pole vessel impedes drainage. The pelvis dilates while the ureter beyond stays normal calibre — the imaging signature.

Golden rule

Prove obstruction with a renogram, treat for symptoms/stones/infection/function loss, and account for a crossing vessel — pyeloplasty is the gold-standard repair.

Pathophysiology

Mechanism pathway

Tap any step to see why it happens.

Presentation

Symptom sorter

The common presentation.

Intermittent flank pain, classically worse after fluids/alcohol (diuresis)Antenatal/childhood hydronephrosis (congenital)Incidental dilated pelvis
Work-up

Diagnostic algorithm

Each step answers one question. Tap to expand.

Management

Treatment ladder

Repair obstruction that causes symptoms, stones, infection or function loss; otherwise observe stable, well-functioning systems.

1
Prove obstruction + function
2
Observe if asymptomatic/well-functioning
3
Pyeloplasty for indications (vessel-aware)
4
Endopyelotomy only without a crossing vessel
5
Surveillance after repair
Procedures

Procedure chooser

Surgical / procedural options
  • Pyeloplasty (open/laparoscopic/robotic) — the gold standard, transposing a crossing vessel
Safety

Complications

Disease complications
  • Stones, infection, progressive function loss
Treatment complications
  • Anastomotic leak/stenosis after pyeloplasty
  • Bleeding if a crossing vessel is missed at endopyelotomy
How to prevent
  • Identify crossing vessels preoperatively
  • Tension-free, well-vascularised anastomosis
How to manage
  • Re-do pyeloplasty for restenosis
  • Stent/nephrostomy for leak
Surveillance

Follow-up

What to monitor
  • Symptom resolution
  • Differential function on renography
  • Drainage
Timing
  • Post-repair renogram to confirm improved drainage
Success looks like
  • Relieved obstruction, stable/improved function, no pain
Failure looks like
  • Persistent obstruction or recurrent stenosis
When to image
  • Symptoms; surveillance renography
Long-term issues
  • Restenosis; function loss if untreated
Safety

Red flags

Infection with obstruction
Declining differential function
Single kidney
Reference

Summary tables

UPJ obstruction essentials

ItemDetail
HallmarkDilated pelvis, normal-calibre ureter
ConfirmDiuretic (MAG3) renogram
PitfallLower-pole crossing vessel
Gold-standard repairPyeloplasty
Recall

Memory hooks

Dilated pelvis + normal ureter = UPJ.

Pain after fluids/alcohol (diuresis).

Prove it with a diuretic renogram.

Crossing vessel → pyeloplasty, not endopyelotomy.

Exam

Board traps

Diuresis-related flank pain with a dilated pelvis and normal ureter — UPJ obstruction.

Crossing vessel missed before endopyelotomy.

Well-functioning asymptomatic dilation operated unnecessarily.

Apply

Clinical cases

Case 1

A 24-year-old has recurrent right flank pain after drinking, with a dilated renal pelvis but a normal ureter; CT angiography shows a lower-pole crossing vessel.

What is the diagnosis and the preferred treatment?

Test yourself

Quiz

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